SKU: 91652159872

OTR-AC (MK-29, OSTARINE-O-ACETATE) Powder, 1gr

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Description

OTR-AC (MK-29, OSTARINE-O-ACETATE) Powder, 1grOTR AC (MK 29, OSTARINE O ACETATE) OTR AC, also known as MK 2866 Ester, is MK 2866 (Ostarine) that has undergone esterification (the process of combining an organic acid with an alcohol). This chemical process is used to maximize potency and extend the half life (the time required for a quantity to reduce to half of its initial value) of a substance. Due to this process, the ester version of ostarine has the capacity to remain bioactive ten times

OTR-AC (MK-29, OSTARINE-O-ACETATE)

OTR-AC, also known as MK-2866 Ester, is MK-2866 (Ostarine) that has undergone esterification (the process of combining an organic acid with an alcohol). This chemical process is used to maximize potency and extend the half-life (the time required for a quantity to reduce to half of its initial value) of a substance. Due to this process, the ester version of ostarine has the capacity to remain bioactive ten times longer. This results in benefits such as reduced dosing frequency and more stable blood levels.

How OTR-AC Works 
As the ester version of the selective androgen receptor modulator (SARM) ostarine, OTR-AC is more potent and has longer-lasting effects. By binding to proteins in the body known as androgen receptors, it stimulates the formation of muscle tissue. This, in turn, leads to an increase in muscle mass and strength.

Research on OTR-AC
Increase in Muscle Mass and Strength 
Studies suggest that OTR-AC, along with other SARMs, increases muscle mass and strength by stimulating the formation of muscle tissue:

  • In adult rats, the administration of SARMs, including OTR-AC, resulted in an increase in lean muscle mass and a decrease in body fat percentage.
  • In older male and female rats, OTR-AC administration resulted in increased lean muscle mass, decreased fat mass, and significant improvements in their ability to climb stairs.
  • Studies showed that OTR-AC may help increase muscle mass in rats with cancer cachexia (muscle wasting).
  • In older male and female rats, OTR-AC significantly improved total lean body mass and physical function.
  • In rats that had their ovaries surgically removed, OTR-AC improved muscle tissue.
  • In rats, OTR-AC increased muscle mass by enhancing the production of muscle cells.

Reduction of Body Fat 
Aside from helping gain muscle mass, OTR-AC has also been found to reduce overall body fat:

  • In Phase I and II clinical trials, OTR-AC has demonstrated promising results in increasing total lean body mass, decreasing total tissue fat percentage, and enhancing functional performance.
  • A review of studies showed that OTR-AC can help increase lean body mass and reduce body fat in overweight rats.
  • In a phase 2a study, the administration of OTR-AC along with other SARMs resulted in increased lean fat mass and decreased body fat percentage.
  • In male rats, OTR-AC increased fat cell breakdown by improving lipid metabolism and affecting the release of adiponectin (a hormone that regulates fatty acid breakdown).

Improvement of Bone Health 
Studies suggest that OTR-AC can help stimulate bone formation and protect against bone disorders:

  • In rats that had their ovaries surgically removed, OTR-AC administration resulted in improved bone healing.
  • In a rat model for aged male osteoporosis, both OTR-AC and testosterone treatments improved bone healing by increasing callus volume and area, bone volume and density, and bone width.
  • In a rat model of postmenopausal osteoporosis, high doses of OTR-AC for 5 weeks resulted in increased bone volume, density, and bone mineral density.

 

Reduction of Cholesterol Levels 
Evidence suggests that OTR-AC can help lower cholesterol levels, especially low-density lipoprotein (bad cholesterol):

  • In older male and female rats, OTR-AC administration resulted in a significant reduction in low-density lipoprotein levels.
  • In rats that had their ovaries surgically removed, OTR-AC treatment reduced blood cholesterol levels.

Half Life
24 hours.

DISCLAIMER
This material is sold for use in laboratory research only. Terms of sale apply. Not for human consumption, nor for medical, veterinary use. Please use with our DISCLAIMER before ordering.

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SKU: 91652159872

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A
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ARAW
Cuba, US
★★★★★ 5
Great chew toy to keep around the house
Color: Blue/Medium, Size: Blue, Color: Blue/Medium, Size: Blue
This came highly recommended by the behavioural team at the animal shelter and it hasn't disappointed. It's interesting reading the reviews, because our power-chewer pit-mix who can get a chunk off a split antler in a matter of minutes, hasn't ever been able to get a bite out of this bone! This is a great play toy for her, because it's soft enough that we can throw it for her to fetch in the house without worrying about breaking/denting something and are able to pull it out of her mouth fairly easily once she brings it back (still hasn't learned "drop it!"). The bone isn't flavored, so she'll rarely go to it on her own to chew on, but we keep it near the couch so if she ever gets bitey, we have it close at hand to offer to her as a chewer. It's also entertaining to tuck it into her collar and have her figure out how to remove it to play with it (see photo for this game and size compared to 50lb mutt).
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on August 15, 2017
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Verified Purchase
Britney
New York, US
★★★★★ 5
Best bouncy bone!
Color: Orange/Large, Size: Orange, Color: Orange/Large, Size: Orange
My pups love these bones! They are soft and rubbery, but very durable. Had them for a little over 6 months and it has survived my extreme chewers and many tug of war games, and only has a few puncture marks! They bounce on my concrete floors and my pup loves to play fetch with this. Great purchase
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Reviewed in the United States on April 27, 2025
A
Verified Purchase
Amazon Customer
Grantham, US
★★★★★ 4
Excellent for aggressive chewers
Color: Blue/Medium, Size: Blue
First I would like to say I think Jolly Pets are the best line of dog toys out there if you have an aggressive chewer. Their products have amazed me! And I am not being paid for this review. I have a 155 lb mastiff that is an excellent behaved boy but loves to destroy his toys. I had this bone in large and it held up excellent for about 4-5 months. I ordered it again in medium size by mistake and after 2 weeks it already has pieces missing...my fault. My only complaint is the medium size in blue smells like vanilla perfume. I can't wash it off. Although my handsome boy doesn't seem to mind. I just reordered in large. Also ordered a few other Jolly Pet toys as I am amazed at how they hold up. The "soccer ball" is my dogs favorite. It reinflates itself again and again no matter how much chewing or wear and tear its given. It's just magic!
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Reviewed in the United States on October 1, 2022
A
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Annie Sameuchay
Omaha, US
★★★★★ 5
This company makes great toys for pitts!!
Color: Blue/Medium, Size: Blue, Color: Blue/Medium, Size: Blue
Our pitt LOVES this toy. The rubber is reeeaally tough. It’s well designed because it’s a slippery surface. You can tell from the video there’s a lot of squeaking from him trying to get a good grip. He found a pretty good spot to hook his upper teeth into the crevasse, but his bottom teeth kept slipping. As a side note, I wouldn’t leave any toy home alone with him that’s about 3 inches or smaller because dogs can choke on it, but that doesn’t make this any toy or company any less amazing. For toys I would leave home with a power chewer, take a look at that 4inch red ball made by this same company. He hasn’t made a dent in that thing and you can put treats in it. :)
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Reviewed in the United States on March 5, 2025
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Amazon Customer
Los Angeles, US
★★★★★ 1
No for aggressive chewer waste of money
Color: Blue/Medium, Size: Blue, Color: Blue/Medium, Size: Blue
Within 10 minutes she destroyed it
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Reviewed in the United States on June 1, 2026

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